Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953428 | 0.88 | MAPT (0.37) | KIF11MGLLKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL27241189 | 0.82 | CA2 (0.46) | KIF11KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29595177 | 0.80 | MAPT (0.44) | MAPT | |
| SCHEMBL2399704 | 0.80 | MAPT (0.44) | MAPT | |
| SCHEMBL29410834 | 0.79 | ENPP2 (0.41) | MGLLMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4288 | 0.79 | ENPP2 (0.41) | MGLLMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL187809 | 0.78 | CA2 (0.41) | MGLLNOTUMLMNAP2RX7 | |
| SCHEMBL31156210 | 0.78 | TAS2R14 (0.41) | MGLLNOTUMALDH1A1P2RX7 | |
| SCHEMBL1669643 | 0.78 | HSD11B1 (0.40) | MGLLMEN1KMT2ANOTUMLMNA | |
| SCHEMBL29525986 | 0.78 | MGLL (0.38) | MGLLNOTUMP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |