SCHEMBL476028

SCHEMBL476028

O=Cc1ccc2cccc(O)c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.53
RAB9A P51151 2/20 0.50
KDM4E B2RXH2 1/20 0.50
PTGS2 P35354 1/20 0.50
CYP1A2 P05177 1/20 0.48
ERN1 O75460 2/20 0.47
GRIN2D O15399 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
ALDH1A1 P00352 3/20 0.42
ALDH5A1 P51649 3/20 0.42
ABAT P80404 3/20 0.42
AOX1 Q06278 1/20 0.42
TRIM24 O15164 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
KIF11 P52732 1/20 0.41
UNG P13051 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957506 1.00 CTDSP1 (0.53) CTDSP1RAB9AKDM4EPTGS2CYP1A2
SCHEMBL9098185 0.85 PLAU (0.53) RAB9AKDM4EPTGS2CYP1A2GRIN2D
SCHEMBL11963906 0.81 CTDSP1 (0.53) CTDSP1KDM4ECYP1A2ERN1GRIN2D
SCHEMBL9883875 0.78 KIF11 (0.42) RAB9AKDM4EPTGS2ERN1ALDH1A1
SCHEMBL15625133 0.78 CD74 (0.55) CTDSP1RAB9AKDM4EPTGS2CYP1A2
SCHEMBL17988341 0.78 KDM4E (0.59) CTDSP1KDM4ECYP1A2GRIN2DGRIN2A
SCHEMBL5617799 0.78 ALDH1A1 (0.56) RAB9AKDM4ECYP1A2ERN1ALDH1A1
SCHEMBL3257311 0.77 CYP2A6 (0.57) RAB9ACYP1A2ALDH1A1TRIM24HPGD
SCHEMBL4102305 0.77 ALDH1A1 (0.50) RAB9AKDM4EPTGS2CYP1A2ALDH1A1
SCHEMBL5381553 0.77 PTGER4 (0.50) RAB9AKDM4EPTGS2ERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3929207-B1 PEPTIDE FTTFTVT FOR USE IN TREATING FIBROSIS UNIV TEXAS (US) 2024-07-17 EP claimed
EP-3929207-A1 INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES Board of Regents, The University of Texas System (US) 2021-12-29 EP claimed
US-20180086791-A1 INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES UNIV TEXAS (US) 2018-03-29 US claimed
WO-2025033019-A1 COMPOUND, COMPOSITION, METHOD FOR EXPRESSING SENSITIZING EFFECT, AND PRODUCTION METHOD 三菱瓦斯化学株式会社 2025-02-13 WO disclosed
WO-2024214321-A1 COMPOUND, COMPOSITION, METHOD FOR EXPRESSING SENSITIZING EFFECT, AND METHOD FOR PRODUCING SAME 三菱瓦斯化学株式会社 2024-10-17 WO disclosed
EP-3929207-B1 PEPTIDE FTTFTVT FOR USE IN TREATING FIBROSIS UNIV TEXAS (US) 2024-07-17 EP disclosed
US-20240067713-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CHRONIC LUNG DISEASES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-02-29 US disclosed
US-20240059736-A1 INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-02-22 US disclosed
US-11905336-B2 Modified peptide fragments of CAV-1 protein and the use thereof in the treatment of fibrosis LUNG THERAPEUTICS, INC. (US) 2024-02-20 US disclosed
US-20240018186-A1 MODIFIED PEPTIDE FRAGMENTS OF CAV-1 PROTEIN AND THE USE THEREOF IN THE TREATMENT OF FIBROSIS LUNG THERAPEUTICS, INC. (US) 2024-01-18 US disclosed
WO-2024015857-A2 MODIFIED CAVEOLIN-1 PEPTIDE FORMULATIONS AND METHODS OF MANUFACTURING AND USE THEREOF LUNG THERAPEUTICS, INC. (US) 2024-01-18 WO disclosed
WO-2002064621-A2 HISTIDINE PROLINE RICH GLYCOPROTEIN (HPRG) AS AN ANTI-ANGIOGENIC AND ANTI-TUMOR AGENT ATTENUON, LLC (US) 2002-08-22 WO disclosed
WO-2002014369-A2 HUMAN KININOGEN D5 DOMAIN POLYPEPTIDES AND THEIR USE ATTENUON, LLC (US) 2002-02-21 WO disclosed
WO-2001098343-A2 CONSERVED DIAPHANOUS-RELATED FORMIN AUTOREGULATORY DOMAIN (DAD) VAN ANDEL INSTITUTE (US) 2001-12-27 WO disclosed
US-5994309-A OCTAPEPTIDE; ANTITUMOR AGENT ANGSTROM PHARMACEUTICALS, INC. (US) 1999-11-30 US disclosed
EP-0950096-A1 ANTI-INVASIVE AND ANTI-ANGIOGENIC UROKINASE FRAGMENTS AND THEIR USE Angstrom Pharmaceuticals, inc. (US) 1999-10-20 EP disclosed
WO-1999005263-A1 ANTI-INVASIVE AND ANTI-ANGIOGENIC UROKINASE FRAGMENTS AND THEIR USE ANGSTROM PHARMACEUTICALS, INC. (US) 1999-02-04 WO disclosed
EP-0254578-B1 ANTIBIOTIC INTERMEDIATES ELI LILLY AND COMPANY (US) 1993-09-08 EP disclosed
US-4772694-A Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates ELI LILLY AND COMPANY (US) 1988-09-20 US disclosed
EP-0254578-A1 Antibiotic intermediates ELI LILLY AND COMPANY (US) 1988-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086791-A1 INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES IGFBP4, FN1, MDM2 CTDSP1 681/4885RAB9A 3391/4885KDM4E 1941/4885
US-20240059736-A1 INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES IGFBP4, FN1, MDM2 CTDSP1 681/4885RAB9A 3391/4885KDM4E 1941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.