Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292809 | 0.83 | RECQL (0.41) | HSD17B1HSD17B2ACHESIGMAR1LMNA | |
| SCHEMBL29955310 | 0.80 | HTR7 (0.44) | HTR7ACHENPC1ALDH1A1RAB9A | |
| SCHEMBL27740033 | 0.80 | ALDH1A1 (0.55) | HTR7HSD17B1HSD17B2LMNAALDH1A1 | |
| Water SCHEMBL27763066 | 0.79 | ALOX15 (0.31) | — | |
| SCHEMBL11700574 | 0.79 | ALDH1A1 (0.44) | LMNAALDH1A1HTTPOLBMAPT | |
| SCHEMBL3928290 | 0.78 | CA12 (0.47) | ALDH1A1RAB9AHTTGLAMEN1 | |
| SCHEMBL13475062 | 0.78 | ACHE (0.48) | HTR7HSD17B1HSD17B2ACHEICMT | |
| SCHEMBL11138993 | 0.78 | HTR7 (0.51) | HTR7HSD17B1HSD17B2ACHEICMT | |
| SCHEMBL12837169 | 0.77 | MTNR1A (0.54) | HSD17B1HSD17B2UTS2R | |
| SCHEMBL7744950 | 0.77 | ALDH1A1 (0.43) | LMNAALDH1A1HTTPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |