Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852768 | 0.89 | LIPE (0.54) | LIPEENPP2RIPK1HTR2CALDH1A1 | |
| SCHEMBL29956819 | 0.89 | LIPE (0.54) | LIPEENPP2RIPK1HTR2CALDH1A1 | |
| SCHEMBL29957281 | 0.84 | LIPE (0.50) | LIPEENPP2RIPK1MCHR1HTR2C | |
| SCHEMBL13722614 | 0.83 | HTR2A (0.45) | DHFRDCPSBRD4HTR2CXDH | |
| SCHEMBL29956630 | 0.81 | XDH (0.41) | DHFRDCPSBRD4XDHSCN9A | |
| SCHEMBL29659961 | 0.77 | RIPK1 (0.51) | DHFRDCPSRIPK1BRD4MCHR1 | |
| SCHEMBL29957952 | 0.77 | BRD4 (0.47) | LIPEBRD4ALDH1A1GLA | |
| SCHEMBL29955450 | 0.77 | HTR2A (0.39) | LIPERIPK1HTR2C | |
| SCHEMBL2552732 | 0.76 | KAT2B (0.56) | LIPEENPP2 | |
| SCHEMBL29950875 | 0.75 | HRH3 (0.48) | LIPEBRD4ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |