Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953902 | 0.87 | PTGDR2 (0.41) | XDHNPC1RAB9AHPGDLMNA | |
| SCHEMBL29954206 | 0.86 | PTGDR2 (0.43) | XDHNPC1RAB9AHPGDLMNA | |
| SCHEMBL13722614 | 0.85 | HTR2A (0.45) | XDHDHFRDCPSBRD4GRM4 | |
| SCHEMBL29953556 | 0.81 | LIPE (0.47) | XDHDHFRDCPSGLABRD4 | |
| SCHEMBL20870452 | 0.81 | RORC (0.49) | XDHSYKPTGER1NPC1RAB9A | |
| SCHEMBL10196592 | 0.80 | ACHE (0.49) | XDHSYKNPC1RAB9AKDM4E | |
| SCHEMBL29953399 | 0.78 | RAB9A (0.50) | PTGER1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL17708411 | 0.78 | XDH (0.57) | XDHSYK | |
| SCHEMBL29955998 | 0.77 | RAB9A (0.46) | PTGER1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL20206745 | 0.77 | GRM2 (0.47) | SYKPTGER1DHFRDCPSBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |