Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956964 | 0.85 | ENPP2 (0.41) | ENPP2CYP11B1KDM4EALDH1A1MAPT | |
| SCHEMBL8802961 | 0.83 | DCPS (0.47) | CYP11B1NR4A2FFAR1 | |
| SCHEMBL15331303 | 0.80 | FFAR1 (0.48) | ENPP2RAB9ANR4A2NPC1KDM4E | |
| SCHEMBL8807012 | 0.80 | MAOB (0.49) | CYP11B1RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL9076409 | 0.80 | MAPT (0.49) | CYP11B1RAB9ANR4A2NPC1TSHR | |
| SCHEMBL29955054 | 0.76 | ENPP2 (0.51) | ENPP2KDM4EALDH1A1 | |
| SCHEMBL4058607 | 0.75 | MAPT (0.47) | CYP11B1RAB9ANPC1TSHRALDH1A1 | |
| SCHEMBL29953237 | 0.74 | LIPE (0.50) | ENPP2CYP11B1KDM4EALDH1A1GAA | |
| SCHEMBL2562445 | 0.73 | SMPD1 (0.59) | ENPP2CYP11B1RAB9A | |
| SCHEMBL4061725 | 0.72 | LMNA (0.44) | CYP11B1RAB9ANPC1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |