Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954558 | 0.85 | ENPP2 (0.41) | ENPP2CYP11B1FFAR1KDM4EALDH1A1 | |
| SCHEMBL8804838 | 0.81 | NPC1 (0.48) | CYP11B1KDM4EALDH1A1XDHTLR8 | |
| SCHEMBL8803373 | 0.81 | ALDH1A1 (0.47) | CYP11B1FFAR1ALDH1A1MAOBMAPT | |
| SCHEMBL4061725 | 0.81 | LMNA (0.44) | CYP11B1FFAR1KDM4EALDH1A1MAOB | |
| SCHEMBL4058607 | 0.81 | MAPT (0.47) | CYP11B1ALDH1A1MAPT | |
| SCHEMBL15331327 | 0.78 | FFAR1 (0.58) | ENPP2FFAR1CA1CA2KDM4E | |
| SCHEMBL29953237 | 0.77 | LIPE (0.50) | ENPP2CYP11B1KDM4EALDH1A1PLCG1 | |
| SCHEMBL8802961 | 0.75 | DCPS (0.47) | CYP11B1FFAR1MAOB | |
| SCHEMBL29951321 | 0.74 | CA1 (0.46) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL929363 | 0.72 | CYP11B1 (0.49) | CYP11B1KDM4EALDH1A1PLCG1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |