SCHEMBL29954856

SCHEMBL29954856

[C-]#[N+]C(c1ccc([N+](=O)[O-])cc1)S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.53
HSD17B10 Q99714 1/20 0.53
BCHE P06276 1/20 0.46
PKM P14618 1/20 0.45
KMT2A Q03164 7/20 0.43
RAB9A P51151 3/20 0.43
HSP90AA1 P07900 1/20 0.43
CXCR5 P32302 1/20 0.43
APLNR P35414 1/20 0.43
CCR6 P51684 1/20 0.43
GFER P55789 1/20 0.43
CA9 Q16790 5/20 0.43
MEN1 O00255 4/20 0.43
CA12 O43570 4/20 0.41
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA14 Q9ULX7 4/20 0.41
CA3 P07451 3/20 0.41
CA4 P22748 3/20 0.41
CA6 P23280 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956006 0.87 GAA (0.45) ACHEBCHERAB9ACA9CA12
SCHEMBL29951097 0.83 HTT (0.48) ACHEHSD17B10KMT2AMEN1CA2
SCHEMBL4799859 0.80 ALDH1A1 (0.42) ACHEBCHEKMT2ACA9MEN1
SCHEMBL4802706 0.80 RAPGEF4 (0.39) ACHEBCHEKMT2ARAB9ACA9
SCHEMBL992209 0.80 ACHE (0.42) ACHEBCHEKMT2AMEN1ALDH1A1
SCHEMBL29956135 0.80 UTS2R (0.43) ACHEBCHEKMT2AMEN1ALDH1A1
SCHEMBL408195 0.80 NPY2R (0.47) ACHEBCHEPKMKMT2ARAB9A
SCHEMBL4797196 0.78 ALDH1A1 (0.50) ACHEBCHEPKMKMT2ARAB9A
SCHEMBL29954292 0.78 MMP2 (0.41) RAB9ACA9CA12CA1CA2
SCHEMBL29952766 0.78 ALDH1A1 (0.48) HSD17B10KMT2ARAB9AGFERCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed