Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.41 |
| ▸ | TTR | P02766 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900659 | 0.73 | CYP3A4 (0.50) | TTRMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL855530 | 0.73 | ENPP2 (0.41) | ENPP2MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL1317903 | 0.73 | TRPV4 (0.52) | ENPP2 | |
| SCHEMBL14120471 | 0.72 | TRPV4 (0.52) | ENPP2TTR | |
| SCHEMBL952362 | 0.72 | ALDH1A1 (0.45) | MEN1ALDH1A1TP53CYP3A4MAPT | |
| SCHEMBL2521376 | 0.72 | TTR (0.48) | ENPP2TTRMEN1ALDH1A1CYP3A4 | |
| SCHEMBL20286649 | 0.70 | HSD17B10 (0.52) | ENPP2TTRMEN1ALDH1A1CYP3A4 | |
| SCHEMBL15850516 | 0.70 | VCAM1 (0.40) | TTRMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL12327390 | 0.70 | ALDH1A1 (0.41) | ENPP2TTRALDH1A1 | |
| SCHEMBL2377148 | 0.70 | ENPP2 (0.52) | ENPP2TTRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |