Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354834 | 0.84 | CYP1A2 (0.43) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL27363641 | 0.79 | TDP1 (0.49) | MTNR1AMTNR1BKMT2AALDH1A1MEN1 | |
| SCHEMBL11756005 | 0.75 | MTNR1A (0.50) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL27568828 | 0.74 | TSHR (0.56) | CYP1A2KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL5292610 | 0.74 | MTNR1A (0.49) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL9900712 | 0.74 | GAA (0.58) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL19725364 | 0.74 | GAA (0.58) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| Acetic Acid SCHEMBL27465373 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| Acetic Acid SCHEMBL359202 | 0.72 | MTNR1A (0.51) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL4564099 | 0.72 | LDHA (0.52) | MTNR1AMTNR1BGAACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |