Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789950 | 1.00 | MAOA (1.00) | MAOANPC1RAB9AMEN1KMT2A | |
| SCHEMBL3661536 | 0.91 | NPC1 (0.83) | MAOANPC1RAB9AMEN1KMT2A | |
| SCHEMBL394209 | 0.90 | MAOA (1.00) | MAOANPC1RAB9AMEN1KMT2A | |
| SCHEMBL7107987 | 0.90 | MAOA (0.81) | MAOANPC1RAB9AMEN1KMT2A | |
| SCHEMBL31260258 | 0.90 | MAOA (0.81) | MAOANPC1RAB9AMEN1KMT2A | |
| SCHEMBL7331388 | 0.88 | KDM4E (0.86) | MAOANPC1RAB9AMEN1KMT2A | |
| SCHEMBL7227675 | 0.88 | MAOA (0.78) | MAOANPC1RAB9AMEN1KMT2A | |
| SCHEMBL7236943 | 0.88 | MAOA (0.78) | MAOANPC1RAB9AMEN1KMT2A | |
| Ethylene SCHEMBL18528476 | 0.87 | MAOA (0.94) | MAOANPC1RAB9AMEN1KMT2A | |
| SCHEMBL20317211 | 0.87 | NPC1 (0.77) | MAOANPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624214-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-12595370-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2026-04-07 | — | — | US | disclosed |
| US-20240067825-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2024-02-29 | — | — | US | disclosed |
| US-11820899-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| EP-4219632-A2 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | Johnson & Johnson Vision Care, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116355127-A | Polymerizable absorbers for UV and high energy visible light | 强生视力健公司 | 2023-06-30 | — | — | CN | disclosed |
| EP-3759171-B9 | AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2023-05-24 | — | — | EP | disclosed |
| EP-3759171-B1 | AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2023-02-22 | — | — | EP | disclosed |
| CN-111801389-B | Polymerizable absorbers for UV and high energy visible light | 强生视力健公司 | 2023-01-20 | — | — | CN | disclosed |
| US-20220340760-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595370-B2 | Polymerizable absorbers of UV and high energy visible light | NLRP3, NLRP1, XDH | MAOA 871/4885NPC1 3857/4885RAB9A 4881/4885 |
| US-12624214-B2 | Polymerizable absorbers of UV and high energy visible light | CRY1, SCNN1G, MALT1 | MAOA 2139/4885NPC1 3105/4885RAB9A 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.