Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335786 | 1.00 | ALDH1A1 (0.63) | ALDH1A1NPSR1BCHEACHESMN1; SMN2 | |
| SCHEMBL3633382 | 0.82 | HCAR3 (0.56) | ALDH1A1BCHEACHESMN1; SMN2LMNA | |
| SCHEMBL8985656 | 0.82 | KAT2B (0.64) | ALDH1A1NPSR1BCHEACHESMN1; SMN2 | |
| SCHEMBL9725410 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1BCHEACHESMN1; SMN2 | |
| SCHEMBL9725442 | 0.81 | ALDH1A1 (0.59) | ALDH1A1NPSR1BCHEACHESMN1; SMN2 | |
| SCHEMBL29959789 | 0.79 | MAPT (0.60) | ALDH1A1SMN1; SMN2LMNARECQLTDP1 | |
| SCHEMBL14334902 | 0.79 | MAPT (0.60) | ALDH1A1SMN1; SMN2LMNARECQLTDP1 | |
| SCHEMBL1594797 | 0.79 | ALDH1A1 (0.72) | ALDH1A1NPSR1BCHEACHESMN1; SMN2 | |
| SCHEMBL12959657 | 0.78 | KAT2B (0.69) | ALDH1A1LMNAMAPTKAT2B | |
| SCHEMBL15666204 | 0.78 | LMNA (0.79) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3586632-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE OF SAME | TRIOPTOTEC GMBH (DE) | 2022-09-28 | — | — | EP | disclosed |