Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009538 | 0.95 | PLA2G2A (0.53) | KMT2APLA2G2AMEN1P2RX4CNR2 | |
| SCHEMBL4094014 | 0.89 | TP53 (0.52) | KMT2ARAB9ACNR2FAAHPOLB | |
| SCHEMBL3006654 | 0.88 | POLB (0.53) | RAB9ASMN1; SMN2CNR2FAAHCNR1 | |
| SCHEMBL2991276 | 0.86 | ALDH1A1 (0.57) | KMT2APLA2G2AMEN1CNR2FAAH | |
| SCHEMBL3009812 | 0.84 | POLB (0.50) | KMT2APLA2G2AMEN1RAB9ANPC1 | |
| SCHEMBL4382618 | 0.83 | PLA2G2A (0.49) | KMT2APLA2G2AMEN1FAAHLMNA | |
| SCHEMBL2998814 | 0.83 | LMNA (0.51) | RAB9ANPC1SMN1; SMN2CNR2FAAH | |
| SCHEMBL4083920 | 0.81 | ALDH1A1 (0.60) | KMT2APLA2G2AMEN1FAAHLMNA | |
| SCHEMBL4089843 | 0.79 | MAPT (0.47) | KMT2AMEN1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL4083893 | 0.79 | CNR2 (0.50) | KMT2AMEN1RAB9ACNR2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118503-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. | 2009-05-07 | — | — | US | claimed |
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| US-20100197708-A1 | INDOLE COMPOUNDS | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2010-08-05 | — | — | US | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197708-A1 | INDOLE COMPOUNDS | IDO1, IDO2, TPH2 | KMT2A 2233/4885PLA2G2A 3285/4885MEN1 3970/4885 |
| US-20090118503-A1 | FAAH INHIBITORS | FAAH, FAAH2, CNR2 | KMT2A 2103/4885PLA2G2A 242/4885MEN1 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.