Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 9/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | STAT6 | P42226 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Psilostachyin A SCHEMBL31697973 | 1.00 | PTGS2 (1.00) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| Coronopilin SCHEMBL8422737 | 0.72 | PAX8 (1.00) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| SCHEMBL4067330 | 0.67 | PAX8 (0.61) | PTGS2PAX8PKMNLRP3MAPT | |
| Hymenin SCHEMBL29711376 | 0.67 | PAX8 (0.58) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| Parthenin SCHEMBL382003 | 0.67 | PAX8 (0.58) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| Hymenin SCHEMBL12355327 | 0.67 | PAX8 (0.58) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| Hymenin SCHEMBL11892893 | 0.67 | PAX8 (0.58) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| SCHEMBL4067886 | 0.65 | PAX8 (0.59) | PTGS2PAX8PKMNLRP3MAPT | |
| SCHEMBL4058769 | 0.64 | PAX8 (0.55) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| SCHEMBL21563386 | 0.62 | PAX8 (0.50) | PTGS2PAX8PKMNLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143938-B | Alpha-exo-methylene-lactone compound and application thereof | 暨南大学 | 2022-11-01 | — | — | CN | disclosed |