SCHEMBL21563386

SCHEMBL21563386

C=C1C(=O)OC2C1CCC(C)C1CCCC12C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PAX8 Q06710 1/20 0.50
▸ PTGS2 P35354 3/20 0.45
▸ MITF O75030 1/20 0.37
▸ CYP3A4 P08684 5/20 0.36
▸ LMNA P02545 4/20 0.36
▸ TP53 P04637 4/20 0.36
▸ CYP2D6 P10635 2/20 0.35
▸ NLRP3 Q96P20 2/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ STAT3 P40763 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.35
▸ PKM P14618 2/20 0.35
▸ NFKB1 P19838 2/20 0.35
▸ CYP1A2 P05177 2/20 0.35
▸ STAT6 P42226 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ CASP1 P29466 1/20 0.35
▸ NFKB2 Q00653 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Damsin SCHEMBL18642932 0.75 PTGS2 (0.55) PAX8PTGS2MITFCYP3A4LMNA
Damsin SCHEMBL18642934 0.75 PTGS2 (0.55) PAX8PTGS2MITFCYP3A4LMNA
SCHEMBL21765578 0.74 PAX8 (0.30) PAX8
SCHEMBL29355617 0.73 PAX8 (0.45) PAX8PTGS2TDP1ALDH1A1PKM
SCHEMBL18550778 0.69 PAX8 (0.47) PAX8PTGS2NLRP3PKMMAPT
Ambrosin SCHEMBL3463664 0.68 MAPT (0.54) PAX8PTGS2CYP3A4LMNATP53
Ambrosin SCHEMBL3463663 0.68 MAPT (0.54) PAX8PTGS2CYP3A4LMNATP53
Coronopilin SCHEMBL8422737 0.67 PAX8 (1.00) PAX8PTGS2CYP3A4LMNATP53
SCHEMBL21563385 0.64 UBE2D3 (0.49) PTGS2CYP3A4LMNATP53CYP2D6
SCHEMBL13940415 0.63 PAX8 (0.41) PAX8PTGS2CYP3A4LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224882-A1 LIGHT SOURCE SEOUL VIOSYS CO LTD (KR) 2024-07-11 — — US disclosed
US-20240224882-A1 LIGHT SOURCE SEOUL VIOSYS CO LTD (KR) 2024-07-11 — — US disclosed
US-11778953-B2 Light source for plant cultivation SEOUL VIOSYS CO., LTD. (KR) 2023-10-10 — — US disclosed
US-11778953-B2 Light source for plant cultivation SEOUL VIOSYS CO., LTD. (KR) 2023-10-10 — — US disclosed
US-20220192103-A1 LIGHT SOURCE FOR PLANT CULTIVATION SEOUL VIOSYS CO., LTD. (KR) 2022-06-23 — — US disclosed
US-11021488-B2 Hetero-substituted cyclic lactone analogues and uses thereof BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2021-06-01 — — US disclosed
US-20190345167-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2019-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345167-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF MCL1, BCL9L, DLD PAX8 4324/4885PTGS2 2995/4885MITF 4033/4885
US-11021488-B2 Hetero-substituted cyclic lactone analogues and uses thereof MCL1, BCL9L, DLD PAX8 4324/4885PTGS2 2995/4885MITF 4033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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