Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 9/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | STAT6 | P42226 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Psilostachyin A SCHEMBL29966244 | 1.00 | PTGS2 (1.00) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| Coronopilin SCHEMBL8422737 | 0.72 | PAX8 (1.00) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| SCHEMBL4067330 | 0.67 | PAX8 (0.61) | PTGS2PAX8PKMNLRP3MAPT | |
| Hymenin SCHEMBL29711376 | 0.67 | PAX8 (0.58) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| Parthenin SCHEMBL382003 | 0.67 | PAX8 (0.58) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| Hymenin SCHEMBL12355327 | 0.67 | PAX8 (0.58) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| Hymenin SCHEMBL11892893 | 0.67 | PAX8 (0.58) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| SCHEMBL4067886 | 0.65 | PAX8 (0.59) | PTGS2PAX8PKMNLRP3MAPT | |
| SCHEMBL4058769 | 0.64 | PAX8 (0.55) | PTGS2PAX8PKMNLRP3ALDH1A1 | |
| SCHEMBL21563386 | 0.62 | PAX8 (0.50) | PTGS2PAX8PKMNLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320273-A1 | DECOY CYTOKINE RECEPTOR | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320273-A1 | DECOY CYTOKINE RECEPTOR | IL1RN, IL6ST, IL2RA | PTGS2 1984/4885PAX8 2527/4885PKM 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.