Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877884 | 1.00 | MAOA (0.42) | MAOAMAOBHTR2CHTR2BHTR4 | |
| SCHEMBL2146355 | 0.86 | ALDH1A1 (0.56) | RAB9AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL15942807 | 0.80 | ADORA2A (0.47) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL2919354 | 0.79 | LMNA (0.63) | MAOBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL16053859 | 0.79 | MTOR (0.43) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL4151151 | 0.79 | HRH4 (0.47) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL16188992 | 0.78 | PKM (0.59) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28371344 | 0.77 | RAB9A (0.48) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4159988 | 0.77 | RAB9A (0.48) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL18463239 | 0.77 | GAA (0.41) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260211-B | Thiophene condensed ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-115260211-A | Thiophene fused ring containing derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-01 | — | — | CN | disclosed |