Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458829 | 0.87 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MMP1MMP9MMP3 | |
| SCHEMBL29967257 | 0.86 | MMP1 (0.48) | ALDH1A1L3MBTL1MMP1MMP9MMP3 | |
| SCHEMBL22367341 | 0.86 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MMP1SMN1; SMN2MAPT | |
| SCHEMBL22367311 | 0.84 | MMP1 (0.49) | ALDH1A1L3MBTL1MMP1MMP9MMP3 | |
| SCHEMBL2262766 | 0.82 | CYP3A4 (0.52) | ALDH1A1L3MBTL1MMP1MMP9MMP3 | |
| SCHEMBL29967880 | 0.80 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1MMP1MMP9MMP3 | |
| SCHEMBL29120595 | 0.80 | SIGMAR1 (0.57) | ALDH1A1L3MBTL1MMP1MMP9MMP3 | |
| SCHEMBL26893066 | 0.80 | SIGMAR1 (0.57) | ALDH1A1L3MBTL1MMP1MMP9MMP3 | |
| SCHEMBL29967631 | 0.79 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MMP1MMP9MMP3 | |
| SCHEMBL31570605 | 0.79 | DPP4 (0.52) | ALDH1A1L3MBTL1MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11401270-B2 | Alcoxyamino derivatives for treating pain and pain related conditions | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401270-B2 | Alcoxyamino derivatives for treating pain and pain related conditions | CACNA1B, CACNA1G, CACNA2D2 | ALDH1A1 713/4885L3MBTL1 4623/4885MMP1 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.