Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29968012 | 0.92 | NR1H4 (0.46) | PPARGDCTPP1HIF1AP2RX3KMT2A | |
| SCHEMBL29967830 | 0.91 | PLA2G10 (0.42) | PLA2G10PPARGFABP4CYP2D6CYP2C9 | |
| SCHEMBL29967574 | 0.91 | PPARG (0.41) | PLA2G10PPARGFABP4CYP2D6CYP2C9 | |
| SCHEMBL29968086 | 0.91 | PPARG (0.45) | PLA2G10PPARG | |
| SCHEMBL29967912 | 0.89 | P2RX3 (0.39) | PPARGDCTPP1P2RX3 | |
| SCHEMBL29967971 | 0.86 | PPARG (0.42) | PPARGDCTPP1P2RX3 | |
| SCHEMBL29967938 | 0.84 | PPARG (0.42) | PPARGP2RX3NR1H4 | |
| SCHEMBL29968167 | 0.84 | NR1H4 (0.44) | PPARGDCTPP1P2RX3NR1H4 | |
| SCHEMBL29967688 | 0.83 | CNR2 (0.38) | PPARGP2RX3 | |
| SCHEMBL29968198 | 0.83 | DCTPP1 (0.42) | PPARGDCTPP1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |