Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967971 | 0.93 | PPARG (0.42) | P2RX3PPARGDCTPP1 | |
| SCHEMBL29967905 | 0.91 | P2RX3 (0.38) | P2RX3PPARGPTGDR2CNR2 | |
| SCHEMBL29967492 | 0.91 | TP53 (0.39) | P2RX3PPARGPTGDR2CNR2 | |
| SCHEMBL29967953 | 0.89 | PLA2G10 (0.41) | P2RX3PPARGDCTPP1 | |
| SCHEMBL29968433 | 0.86 | CYP19A1 (0.39) | P2RX3PPARGPTGDR2CNR2 | |
| SCHEMBL29967886 | 0.86 | PPARG (0.40) | P2RX3PPARG | |
| SCHEMBL29968012 | 0.86 | NR1H4 (0.46) | P2RX3PPARGDCTPP1 | |
| SCHEMBL29967688 | 0.85 | CNR2 (0.38) | P2RX3PPARGCNR2 | |
| SCHEMBL29968376 | 0.84 | PPARG (0.41) | P2RX3PPARGCNR2 | |
| SCHEMBL29968198 | 0.83 | DCTPP1 (0.42) | P2RX3PPARGSPHK1DCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |