Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786689 | 0.81 | L3MBTL1 (0.45) | KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1309161 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1KEAP1NFE2L2MAPT | |
| SCHEMBL29975085 | 0.80 | HTR7 (0.56) | KDM4EALDH1A1KEAP1NFE2L2HTR1B | |
| SCHEMBL23579204 | 0.80 | HTR7 (0.56) | KDM4EALDH1A1KEAP1NFE2L2HTR1B | |
| SCHEMBL3783707 | 0.79 | CYP1A2 (0.53) | KDM4EALDH1A1LTA4HL3MBTL1 | |
| SCHEMBL17959491 | 0.79 | PLAU (0.42) | KDM4EALDH1A1HTR1BTAAR1L3MBTL1 | |
| SCHEMBL6712545 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KEAP1NFE2L2HTR1BHTR7 | |
| SCHEMBL10437723 | 0.78 | CYP1A2 (0.47) | KDM4EALDH1A1LTA4HL3MBTL1 | |
| SCHEMBL3785150 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL29973194 | 0.74 | CHRNB2 (0.38) | KDM4EALDH1A1CHRNB2CHRNA4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166028-A | Diaminopuridine-containing thiourea inhibitors of herpes viruses | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |