SCHEMBL29975987

SCHEMBL29975987

C1CCC2=NCCCN2CC1.C1CCC2=NCCCN2CC1.Cc1cn([C@H]2CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@@H](CP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NT5M Q9NPB1 1/20 0.38
TYMP P19971 4/20 0.38
TK1 P04183 6/20 0.36
TK2 O00142 2/20 0.36
RNASE1 P07998 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27157713 0.86 TYMP (0.48) NT5MTYMPTK1TK2RNASE1
SCHEMBL29975279 0.83 TYMP (0.44) NT5MTYMPTK1TK2RNASE1
SCHEMBL29975465 0.80 ABL1 (0.48)
SCHEMBL27157933 0.77 TK1 (0.41) NT5MTYMPTK1RNASE1
SCHEMBL441127 0.77 RNASE1 (0.50) TK1TK2RNASE1
SCHEMBL409820 0.77 RNASE1 (0.50) TK1TK2RNASE1
SCHEMBL29975654 0.76 ABL1 (0.36)
SCHEMBL19660825 0.76 TK1 (0.45) TK1TK2RNASE1
SCHEMBL19953995 0.75 TK1 (0.44) TK1TK2RNASE1
SCHEMBL30177217 0.75 NT5M (0.41) NT5MTK1TK2RNASE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US claimed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP claimed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO claimed
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US disclosed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP disclosed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND POLRMT, CYC1, MRM1 NT5M 2378/4885TYMP 319/4885TK1 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.