Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | CAT | P04040 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671154 | 1.00 | CES2 (0.38) | CES2CES1GPR17KDM4EASPH | |
| SCHEMBL6343820 | 0.83 | CES2 (0.40) | CES2CES1GPR17KDM4EASPH | |
| SCHEMBL31258574 | 0.81 | CES2 (0.47) | CES2CES1KDM4EASPHKDM8 | |
| SCHEMBL365563 | 0.81 | CES2 (0.47) | CES2CES1KDM4EASPHKDM8 | |
| SCHEMBL30632655 | 0.81 | DGAT1 (0.41) | CES2CES1CA1CA2CA9 | |
| SCHEMBL30047468 | 0.81 | KDM4E (0.41) | CES2CES1GPR17KDM4EASPH | |
| SCHEMBL21807887 | 0.81 | CA1 (0.46) | GPR17KDM4EASPHKDM8CA1 | |
| SCHEMBL28052874 | 0.81 | ALDH1A1 (0.38) | CES2CES1CA1CA2LMNA | |
| SCHEMBL10325437 | 0.81 | CES2 (0.37) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL16555805 | 0.81 | DGAT1 (0.41) | CES2CES1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115296-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES | UNIV YALE (US) | 2026-04-30 | — | — | US | disclosed |
| CN-117003670-B | Preparation process of 4-bromo-2, 6-difluorobenzonitrile | 杭州国瑞生物科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-119176772-A | Compound with Mrgpr X receptor inhibition effect and application thereof | 博济医药科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-117003670-A | Preparation process of 4-bromo-2, 6-difluorobenzonitrile | 杭州国瑞生物科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116802181-A | Triazolopyridine compounds as kinase inhibitors | 百时美施贵宝公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-115697975-A | Herbicidal cinnoline derivatives | 先正达农作物保护股份公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20230000994-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES | YALE UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
| CN-115073282-A | Method for rapidly preparing 3-bromo-2, 4-difluorobenzoic acid based on microchannel continuous flow technology | 都创(重庆)医药科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000994-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES | CRBN, ARAF, VHL | CES2 3556/4885CES1 3150/4885GPR17 4465/4885 |
| US-20260115296-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES | CRBN, VHL, ADRM1 | CES2 3298/4885CES1 2403/4885GPR17 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.