Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978374 | 0.91 | RAB9A (0.43) | HDAC6HDAC1HDAC8HDAC5ALDH1A1 | |
| SCHEMBL29977850 | 0.88 | HDAC6 (0.44) | HDAC6HDAC1HDAC8HDAC5ALDH1A1 | |
| SCHEMBL29977961 | 0.88 | ALDH1A1 (0.44) | HDAC6HDAC1HDAC8HDAC5ALDH1A1 | |
| SCHEMBL29978099 | 0.87 | MEN1 (0.52) | HDAC6HDAC1HDAC8HDAC5ALDH1A1 | |
| SCHEMBL29978262 | 0.87 | HDAC6 (0.42) | HDAC6HDAC1HDAC8HDAC5HPGD | |
| SCHEMBL29978400 | 0.86 | HDAC6 (0.45) | HDAC6HDAC1HDAC8HDAC5ALDH1A1 | |
| SCHEMBL29978823 | 0.86 | LMNA (0.46) | HDAC6HDAC1HDAC8HDAC5ALDH1A1 | |
| SCHEMBL29978545 | 0.86 | FKBP1A (0.46) | HDAC6HDAC1HDAC8HDAC5HTT | |
| SCHEMBL29977772 | 0.86 | HDAC6 (0.43) | HDAC6HDAC1HDAC8HDAC5ALDH1A1 | |
| SCHEMBL29978322 | 0.85 | HDAC6 (0.43) | HDAC6HDAC1HDAC8HDAC5HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |