Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549723 | 1.00 | ALOX5 (0.47) | ALOX5ALDH1A1ALOX15MTORMAPT | |
| SCHEMBL28566234 | 1.00 | ALOX5 (0.47) | ALOX5ALDH1A1ALOX15MTORMAPT | |
| SCHEMBL14150723 | 0.85 | ALDH1A1 (0.52) | ALDH1A1ALOX15MAPTHDAC8KDM4E | |
| SCHEMBL5909681 | 0.80 | KDM4E (0.43) | ALOX5ALDH1A1ALOX15MTORMAPT | |
| SCHEMBL3062350 | 0.79 | TRPM8 (0.50) | ALOX5ALDH1A1ALOX15MTORMAPT | |
| SCHEMBL3068504 | 0.79 | TRPM8 (0.50) | ALOX5ALDH1A1ALOX15MTORMAPT | |
| SCHEMBL604822 | 0.79 | TRPM8 (0.50) | ALOX5ALDH1A1ALOX15MTORMAPT | |
| SCHEMBL4245598 | 0.75 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPTHDAC8KDM4E | |
| SCHEMBL4096876 | 0.74 | ALDH1A1 (0.48) | ALDH1A1ALOX15MAPTHDAC8KDM4E | |
| SCHEMBL290437 | 0.74 | POLB (0.44) | ALDH1A1ALOX15MAPTHDAC8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297858-A | Pharmaceutical composition for treating hypertrophic cardiomyopathy and treatment method using same | 赛特瑞恩股份有限公司 | 2022-11-04 | — | — | CN | disclosed |