Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 3/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068504 | 1.00 | TRPM8 (0.50) | TRPM8ALOX15ALDH1A1ALOX5KDM4E | |
| SCHEMBL3062350 | 1.00 | TRPM8 (0.50) | TRPM8ALOX15ALDH1A1ALOX5KDM4E | |
| SCHEMBL6457702 | 0.86 | TRPM8 (0.55) | TRPM8ALDH1A1ALOX5KDM4ENR1I2 | |
| SCHEMBL5805578 | 0.84 | ALOX5 (0.59) | TRPM8ALOX15ALDH1A1ALOX5MYC | |
| SCHEMBL21891698 | 0.83 | ALDH1A1 (0.56) | ALOX15ALDH1A1KDM4EMYCNR4A1 | |
| SCHEMBL28566234 | 0.79 | ALOX5 (0.47) | TRPM8ALOX15ALDH1A1ALOX5KDM4E | |
| SCHEMBL29980356 | 0.79 | ALOX5 (0.47) | TRPM8ALOX15ALDH1A1ALOX5KDM4E | |
| SCHEMBL28549723 | 0.79 | ALOX5 (0.47) | TRPM8ALOX15ALDH1A1ALOX5KDM4E | |
| Phthalic Acid SCHEMBL28418540 | 0.76 | ALDH1A1 (0.78) | ALOX15ALDH1A1KDM4EMYCNR4A1 | |
| Phthalic Acid SCHEMBL28043206 | 0.75 | ALDH1A1 (0.61) | ALOX15ALDH1A1KDM4ETAAR1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12551465-B2 | Pharmaceutical composition for treatment of hypertrophic cardiomyopathy and treatment method using same composition | CELLTRION INC. (KR) | 2026-02-17 | — | — | US | claimed |
| US-20230190708-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION | CELLTRION, INC. (KR) | 2023-06-22 | — | — | US | claimed |
| EP-4140482-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION | Celltrion, Inc. (KR) | 2023-03-01 | — | — | EP | claimed |
| WO-2021215852-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION | (주)셀트리온 (KR) | 2021-10-28 | — | — | WO | claimed |
| EP-2260029-B1 | PREPARATION OF MORPHOLINE DERIVATIVES | SANDOZ AG (CH) | 2014-10-01 | — | — | EP | claimed |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | claimed |
| US-20110009629-A1 | PREPARATION OF MORPHOLINE DERIVATIVES | SANDOZ AG (CH) | 2011-01-13 | — | — | US | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |
| US-12551465-B2 | Pharmaceutical composition for treatment of hypertrophic cardiomyopathy and treatment method using same composition | CELLTRION INC. (KR) | 2026-02-17 | — | — | US | disclosed |
| CN-115297858-B | Pharmaceutical composition for treating hypertrophic cardiomyopathy and treatment method using the same | 赛特瑞恩股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| US-20230190708-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION | CELLTRION, INC. (KR) | 2023-06-22 | — | — | US | disclosed |
| EP-4140482-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION | Celltrion, Inc. (KR) | 2023-03-01 | — | — | EP | disclosed |
| CN-115297858-A | Pharmaceutical composition for treating hypertrophic cardiomyopathy and treatment method using same | 赛特瑞恩股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | disclosed |
| US-20110009629-A1 | PREPARATION OF MORPHOLINE DERIVATIVES | SANDOZ AG (CH) | 2011-01-13 | — | — | US | disclosed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | disclosed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009629-A1 | PREPARATION OF MORPHOLINE DERIVATIVES | OPRK1, TACR1, CMA1 | TRPM8 400/4885ALOX15 926/4885ALDH1A1 1063/4885 |
| US-12551465-B2 | Pharmaceutical composition for treatment of hypertrophic cardiomyopathy and treatment method using same composition | ME2, TNNT2, TNNC1 | TRPM8 788/4885ALOX15 544/4885ALDH1A1 440/4885 |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | ACKR3, KIT, C3AR1 | TRPM8 3562/4885ALOX15 703/4885ALDH1A1 1235/4885 |
| US-20230190708-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION | ATP2A2, CPT1B, TNNT2 | TRPM8 726/4885ALOX15 1767/4885ALDH1A1 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.