Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.76 |
| ▸ | KDM1A | O60341 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL1681355 | 0.93 | HDAC6 (0.68) | HDAC6HDAC1KDM1AALDH1A1KDM4E | |
| SCHEMBL2992964 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EMPOCYP1A2CYP3A4 | |
| SCHEMBL2004792 | 0.82 | ALDH1A1 (0.73) | HDAC6HDAC1ALDH1A1KDM4EMPO | |
| SCHEMBL12472779 | 0.82 | HDAC6 (1.00) | HDAC6HDAC1KDM1AALDH1A1HDAC2 | |
| SCHEMBL3673435 | 0.81 | HDAC6 (0.75) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| Hydrochloric Acid SCHEMBL10704343 | 0.80 | HDAC6 (0.53) | HDAC6HDAC1KDM1AALDH1A1KDM4E | |
| Isoniazid SCHEMBL228 | 0.78 | KDM4E (1.00) | ALDH1A1KDM4EMPOCYP1A2CYP3A4 | |
| Isoniazid SCHEMBL16642161 | 0.78 | KDM4E (1.00) | ALDH1A1KDM4EMPOCYP1A2CYP3A4 | |
| Isoniazid SCHEMBL16642160 | 0.78 | KDM4E (1.00) | ALDH1A1KDM4EMPOCYP1A2CYP3A4 | |
| SCHEMBL1744086 | 0.78 | ALDH1A1 (0.67) | HDAC6HDAC1ALDH1A1KDM4EMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9538759-B2 | Chemical compositions and methodology to enhance plant growth and development | MCDANIEL ROBERT GENE (US) | 2017-01-10 | — | — | US | claimed |
| EP-1841772-B1 | TETRAHYDROFURANE DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES | SANOFI SA (FR) | 2015-05-06 | — | — | EP | claimed |
| US-20150038330-A1 | Chemical Compositions and Methodology to Enhance Plant Growth and Development | MCDANIEL ROBERT GENE (US) | 2015-02-05 | — | — | US | claimed |
| EP-1461010-A2 | HYDROXAMIC ACID AND ITS DERIVATIVES AS INHIBITORS OF MELANOCYTE TYROSINASE FOR TOPICAL SKIN LIGHTENERS | Integriderm, Inc. (US) | 2004-09-29 | — | — | EP | claimed |
| US-20030199558-A1 | Hydroxamic acid and its derivatives as inhibitors of melanocyte tyrosinase for topical skin lighteners | INTEGRIDERM, INC. | 2003-10-23 | — | — | US | claimed |
| WO-2003057184-A2 | HYDROXAMIC ACID AND ITS DERIVATIVES AS INHIBITORS OF MELANOCYTE TYROSINASE FOR TOPICAL SKIN LIGHTENERS | INTEGRIDERM, INC. (US) | 2003-07-17 | — | — | WO | claimed |
| CN-116162055-B | Method for preparing piperidine derivative from pyridine N-oxide derivative | 山东汇智药物研究有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116162055-A | Method for preparing piperidine derivative from pyridine N-oxide derivative | 山东汇智药物研究有限公司 | 2023-05-26 | — | — | CN | disclosed |
| US-20230056785-A1 | GAS-STORING MATERIAL INCLUDING METAL/ORGANIC FRAMEWORK BONDED BY HYDROXAMIC ACID | RIKKYO EDUCATIONAL CORPORATION (JP) | 2023-02-23 | — | — | US | disclosed |
| WO-2021117741-A1 | GAS-STORING MATERIAL INCLUDING METAL/ORGANIC FRAMEWORK BONDED BY HYDROXAMIC ACID | 学校法人立教学院 | 2021-06-17 | — | — | WO | disclosed |
| WO-2019180653-A1 | COMPOSITIONS, MATERIALS, AND METHODS FOR DEACTIVATING TOXIC AGENTS | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (INSTEM) (IN) | 2019-09-26 | — | — | WO | disclosed |
| US-9538759-B2 | Chemical compositions and methodology to enhance plant growth and development | MCDANIEL ROBERT GENE (US) | 2017-01-10 | — | — | US | disclosed |
| US-8877935-B2 | One-pot process for the synthesis of dalfampridine | PROCOS S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |
| US-4608373-A | BACTERICIDES, ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-08-26 | — | — | US | disclosed |
| US-4546176-A | 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same | EISAI CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| EP-0142274-A2 | Cephalosporin compounds and salts thereof, their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1985-05-22 | — | — | EP | disclosed |
| EP-0112164-A2 | Cephem compounds, and their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-06-27 | — | — | EP | disclosed |
| EP-0060144-A2 | Cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4336253-A | Cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4215118-A | BACTERICIDES, ANIMAL GROWTH PROMOTERS, PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199558-A1 | Hydroxamic acid and its derivatives as inhibitors of melanocyte tyrosinase for topical skin lighteners | TYR, MC1R, MITF | HDAC6 647/4885HDAC1 466/4885KDM1A 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.