SCHEMBL30964329

SCHEMBL30964329

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 8/20 0.44
▸ OPRM1 P35372 7/20 0.44
▸ OPRK1 P41145 3/20 0.44
▸ ALDH1A1 P00352 2/20 0.39
▸ MAPT P10636 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7290743 0.89 OPRD1 (0.46) OPRD1OPRM1OPRK1ALDH1A1MAPT
SCHEMBL7290758 0.89 OPRD1 (0.46) OPRD1OPRM1OPRK1ALDH1A1MAPT
SCHEMBL30964325 0.88 FURIN (0.44) OPRD1OPRM1OPRK1
SCHEMBL31518662 0.86 ALDH1A1 (0.49) ALDH1A1MAPTMEN1LMNAKMT2A
SCHEMBL30964330 0.83 SLC15A2 (0.45) —
SCHEMBL11127918 0.83 ALDH1A1 (0.49) OPRD1OPRM1OPRK1ALDH1A1MAPT
SCHEMBL30964328 0.83 GRIN2D (0.43) —
SCHEMBL6367826 0.83 OPRM1 (0.44) OPRD1OPRM1OPRK1ALDH1A1MAPT
SCHEMBL29989920 0.83 OPRD1 (0.48) OPRD1OPRM1OPRK1ALDH1A1MAPT
SCHEMBL6367814 0.83 OPRM1 (0.44) OPRD1OPRM1OPRK1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199698-A1 PEPTIDE AMPHIPHILE COMPOSITIONS AND METHODS OF USE THEREOF Endomimetics LLC 2024-06-20 — — US claimed
US-20240218017-A1 PEPTIDE AMPHIPHILES WITH MODIFIED DEGRADING SEQUENCES AND METHODS OF USE THEREOF Endomimetics LLC 2024-07-04 — — US disclosed
US-20240199698-A1 PEPTIDE AMPHIPHILE COMPOSITIONS AND METHODS OF USE THEREOF Endomimetics LLC 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218017-A1 PEPTIDE AMPHIPHILES WITH MODIFIED DEGRADING SEQUENCES AND METHODS OF USE THEREOF ABHD16A, LIPG, POLQ OPRD1 3240/4885OPRM1 3166/4885OPRK1 3479/4885
US-20240199698-A1 PEPTIDE AMPHIPHILE COMPOSITIONS AND METHODS OF USE THEREOF PLD4, NGLY1, VIP OPRD1 1936/4885OPRM1 2617/4885OPRK1 2872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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