SCHEMBL30002267

SCHEMBL30002267

CC[C@H](NC)C(=O)NCc1ccc(OCc2cccc(Cl)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GID4 Q8IVV7 1/20 0.59
MAOB P27338 5/20 0.54
MAOA P21397 2/20 0.54
ALOX5 P09917 1/20 0.53
RXRA P19793 1/20 0.52
RXRB P28702 1/20 0.52
RXRG P48443 1/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
ALDH1A1 P00352 1/20 0.51
POLB P06746 1/20 0.51
ALOX12 P18054 1/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
FFAR1 O14842 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
FAAH O00519 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30002836 1.00 GID4 (0.59) GID4MAOBMAOAALOX5RXRA
SCHEMBL30001520 0.88 NPC1 (0.53) MAOBMAOANPC1RAB9AALDH1A1
SCHEMBL30002878 0.88 NPC1 (0.53) MAOBMAOANPC1RAB9AALDH1A1
SCHEMBL30001953 0.85 CTSL (0.56) GID4MAOBMAOAALOX5
SCHEMBL29152266 0.85 CTSL (0.56) GID4MAOBMAOAALOX5
SCHEMBL8935332 0.83 GID4 (0.62) GID4MAOBMAOAALOX5RXRA
SCHEMBL8935439 0.80 GID4 (0.61) GID4MAOBMAOAALOX5RXRA
SCHEMBL7395180 0.78 MAOB (0.54) GID4MAOBMAOAALOX5RXRA
SCHEMBL3061396 0.78 MAOB (0.54) GID4MAOBMAOAALOX5RXRA
SCHEMBL8935243 0.78 GID4 (0.74) GID4MAOBMAOAALOX5RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION AMTIXBIO CO., LTD. (KR) 2025-06-26 US claimed
US-20250034085-A1 COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
EP-4349329-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION Amtixbio Co., Ltd. (KR) 2024-04-10 EP claimed
CN-117677382-A Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling 阿米蒂比奥有限公司 2024-03-08 CN claimed
CN-110325509-B Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2024-02-02 CN claimed
WO-2022255801-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION (주)앰틱스바이오 2022-12-08 WO claimed
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION AMTIXBIO CO., LTD. (KR) 2025-06-26 US disclosed
US-20250034082-A1 FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AMTIXBIO CO., LTD. (KR) 2025-01-30 US disclosed
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS AMTIXBIO CO., LTD. (KR) 2025-01-30 US disclosed
US-20250034085-A1 COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION AMTIXBIO CO., LTD. (KR) 2025-01-30 US disclosed
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES AMTIXBIO CO., LTD. (KR) 2025-01-30 US disclosed
EP-4349329-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION Amtixbio Co., Ltd. (KR) 2024-04-10 EP disclosed
CN-117677382-A Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling 阿米蒂比奥有限公司 2024-03-08 CN disclosed
CN-110325509-B Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2024-02-02 CN disclosed
CN-116836083-A Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2023-10-03 CN disclosed
WO-2022255801-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION (주)앰틱스바이오 2022-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES BCAT2, BCAT1, DAO GID4 448/4885MAOB 134/4885MAOA 539/4885
US-20250034082-A1 FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME PEPD, BCAT1, ANPEP GID4 777/4885MAOB 2432/4885MAOA 2029/4885
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS ERG28, BCAT2, AADAT GID4 983/4885MAOB 1969/4885MAOA 1412/4885
US-20250034085-A1 COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION PEPD, PREP, ANPEP GID4 827/4885MAOB 2680/4885MAOA 2181/4885
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION TSLP, IL2RA, TRPC7 GID4 3040/4885MAOB 3904/4885MAOA 4463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.