Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138117 | 0.77 | HTR2A (0.32) | KDM4E | |
| SCHEMBL2750984 | 0.76 | ALDH1A1 (0.34) | PTGS1PTGS2ALDH1A1RAB9ALMNA | |
| SCHEMBL5859161 | 0.75 | GAA (0.52) | PTGS1PTGS2MEN1KMT2AMGLL | |
| SCHEMBL29946847 | 0.75 | GAA (0.52) | PTGS1PTGS2MEN1KMT2AMGLL | |
| SCHEMBL1896817 | 0.71 | CYP3A4 (0.40) | MEN1KMT2AMGLLHPGDKDM4E | |
| SCHEMBL27497687 | 0.68 | NOTUM (0.35) | MEN1KMT2AMGLLALDH1A1NOTUM | |
| SCHEMBL1900818 | 0.68 | RAB9A (0.39) | PTGS1PTGS2MEN1KMT2AMGLL | |
| SCHEMBL2749913 | 0.68 | DRD2 (0.41) | NOTUMTSHR | |
| SCHEMBL12841362 | 0.67 | RAB9A (0.44) | PTGS1PTGS2MEN1KMT2AMGLL | |
| SCHEMBL300208 | 0.67 | KEAP1 (0.42) | MEN1KMT2AMGLLALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004443-A8 | PHENYL METHYL SULFONES WITH ANTI-INFLAMMATORY ACTIVITY AND ANTI-TUMOUR ACTIVITY | UNIVERSITAT DE BARCELONA (ES) | 2012-02-09 | — | — | WO | disclosed |
| WO-2012004443-A1 | PHENYL METHYL SULFONES WITH ANTI-INFLAMMATORY ACTIVITY AND ANTI-TUMOUR ACTIVITY | UNIVERSITAT DE BARCELONA (ES) | 2012-01-12 | — | — | WO | disclosed |