Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494112 | 1.00 | PKM (0.39) | PKMIDO1AGXTP2RX7KMT2A | |
| SCHEMBL29374861 | 0.81 | DPP4 (0.37) | PKMIDO1AGXTKMT2ADPP4 | |
| SCHEMBL156831 | 0.81 | DPP4 (0.37) | PKMIDO1AGXTKMT2ADPP4 | |
| SCHEMBL30149750 | 0.80 | IDO1 (0.40) | IDO1AGXTKDM4EDPP4SMN1; SMN2 | |
| SCHEMBL3307736 | 0.80 | IDO1 (0.40) | IDO1AGXTKDM4EDPP4SMN1; SMN2 | |
| SCHEMBL3711398 | 0.79 | PKM (0.42) | PKMIDO1AGXTP2RX7KMT2A | |
| SCHEMBL3910128 | 0.79 | MPO (0.44) | PKMIDO1AGXTP2RX7DPP4 | |
| SCHEMBL31573752 | 0.79 | PKM (0.42) | PKMIDO1AGXTP2RX7KMT2A | |
| SCHEMBL20560561 | 0.79 | PKM (0.38) | PKMIDO1AGXTP2RX7KMT2A | |
| SCHEMBL30005666 | 0.79 | PKM (0.42) | PKMIDO1AGXTP2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063504-A | Fluoro phenyl phosphate compound, perovskite thin film, perovskite solar cell, preparation method, electric equipment and application | 天合光能股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-108727295-A | A kind of 2- (3- aminophenyls)-benzothiazole derivant and its preparation method and application | 济南大学 | 2018-11-02 | — | — | CN | claimed |
| CN-122010944-A | TBC1D 2-targeted aromatic methyl alkenyl matrine derivative and preparation method and application thereof | 广西大学 | 2026-05-12 | — | — | CN | disclosed |
| EP-4714939-A1 | SULFONAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2026-03-25 | — | — | EP | disclosed |
| EP-4680602-A1 | HETEROCYCLIC COMPOUNDS AS SELECTIVE HDAC6 INHIBITORS | Miralinc Pharma, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-12528803-B2 | Inhibitors of αvβ6 integrin | MORPHIC THERAPEUTIC, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-12459942-B2 | Inhibiting (α-v)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| US-12435078-B2 | Pyridazinones and methods of use thereof | GFB (ABC), LLC (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250282782-A1 | PYRAZOLOPYRAZINE COMPOUNDS AS SHP2 INHIBITORS | GENZYME CORP (US) | 2025-09-11 | — | — | US | disclosed |
| CN-120035578-A | Sulfonamide compound, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| EP-3844162-B1 | INHIBITORS OF ALPHA V BETA6 INTEGRIN | MORPHIC THERAPEUTIC INC (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2002094830-A2 | DIHYDROPYRROLO[1,2-A]INDOLE AND TETRAHYDROPYRIDO[1,2-a]-INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA & CO. (CA) | 2002-11-28 | — | — | WO | disclosed |
| EP-0759026-B1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | WELLCOME FOUND (GB) | 1999-08-18 | — | — | EP | disclosed |
| US-5708033-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS OR ANALGESICS | GLAXO WELLCOME INC. (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0759026-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-02-26 | — | — | EP | disclosed |
| WO-1995030645-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |
| US-4846882-A | HALOBENZYL DERIVATIVES | FMC CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| CN-87100152-A | The compound of weeding | — | 1987-08-12 | — | — | CN | disclosed |
| WO-1987004049-A1 | N-SUBSTITUTED TETRAHYDROPHTHALIMIDE HERBICIDAL COMPOUNDS AND INTERMEDIATES THEREFOR | FMC CORPORATION (US) | 1987-07-16 | — | — | WO | disclosed |
| US-4238611-A | Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepine | SPOFA, UNITED PHARMACEUTICAL WORKS (CS) | 1980-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459942-B2 | Inhibiting (α-v)(β-6) integrin | ITGB6, ITGA6, ITGAV | PKM 4176/4885IDO1 4694/4885AGXT 4228/4885 |
| US-20250282782-A1 | PYRAZOLOPYRAZINE COMPOUNDS AS SHP2 INHIBITORS | PTPN5, PTPN2, PTPRJ | PKM 2659/4885IDO1 2091/4885AGXT 2893/4885 |
| US-12435078-B2 | Pyridazinones and methods of use thereof | PDXK, ATP6V1B1, REN | PKM 77/4885IDO1 952/4885AGXT 433/4885 |
| US-12528803-B2 | Inhibitors of αvβ6 integrin | ITGB2, ITGB6, ITGA2 | PKM 3339/4885IDO1 4512/4885AGXT 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.