Sulfuric Acid

Sulfuric Acid

SCHEMBL30008958

ClC1=NCCN1.ClC1=NCCN1.O=S(=O)(O)O

nearest known ligand 0.41

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C known ✓ P18825 4/20 0.32
ADRA1D known ✓ P25100 4/20 0.32
ADRA1A known ✓ P35348 4/20 0.32
ADRA1B known ✓ P35368 4/20 0.32
ADRA2A known ✓ P08913 3/20 0.32
ADRA2B known ✓ P18089 2/20 0.32
OPRK1 known ✓ P41145 1/20 0.32
RAD52 P43351 1/20 0.41
LMNA P02545 3/20 0.34
RECQL P46063 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CXCR4 P61073 3/20 0.32
MEN1 O00255 1/20 0.32
SLC22A1 O15245 1/20 0.32
SLC22A3 O75751 1/20 0.32
HTR1A P08908 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
HRH2 P25021 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL4689065 1.00 RAD52 (0.41) RAD52LMNARECQLALDH1A1CXCR4
Sulfuric Acid SCHEMBL5200708 0.90 RAD52 (0.35) RAD52LMNARECQLALDH1A1ADRA2C
SCHEMBL2279405 0.85
Sulfuric Acid SCHEMBL15348814 0.73 RAD52 (0.41) RAD52LMNAALDH1A1CXCR4ADRA2C
SCHEMBL12556606 0.70
SCHEMBL560406 0.70
Sulfuric Acid SCHEMBL9290925 0.68 ALDH1A1 (0.46) RAD52LMNAALDH1A1ADRA2CADRA1D
Sulfuric Acid SCHEMBL4063746 0.68 ADRA2A (0.43) RAD52ADRA2CADRA1AADRA2AADRA2B
Sulfuric Acid SCHEMBL588321 0.68 RAD52 (0.38) RAD52LMNAALDH1A1ADRA2ACYP2D6
Sulfuric Acid SCHEMBL5604724 0.67 RAD52 (0.51) RAD52LMNAADRA2CADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263367-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-08-21 US disclosed
EP-4341246-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-03-27 EP disclosed
WO-2022245627-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263367-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES TAS2R40, TAS2R10, TAS2R9 ADRA2C 3827/4885ADRA1D 4160/4885ADRA1A 4620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.