Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868792 | 0.91 | HSD11B1 (0.40) | TSHRNPSR1HSD11B1MGLLLIPG | |
| SCHEMBL30267237 | 0.89 | LIPG (0.40) | TSHRNPSR1LIPG | |
| SCHEMBL29201772 | 0.88 | HSD11B1 (0.39) | TSHRHSD11B1MGLLCCR3 | |
| SCHEMBL29277059 | 0.88 | HSD11B1 (0.39) | TSHRNPSR1HSD11B1MGLLCCR3 | |
| SCHEMBL27123175 | 0.88 | HTR1A (0.39) | TSHRNPSR1LIPG | |
| SCHEMBL25920280 | 0.88 | PRKAG1 (0.40) | TSHRNPSR1HSD11B1MGLLLIPG | |
| SCHEMBL30014221 | 0.87 | ITGB3 (0.38) | TSHRNPSR1HSD11B1MGLLCCR3 | |
| SCHEMBL27125679 | 0.87 | ITGB3 (0.38) | TSHRNPSR1HSD11B1MGLLCCR3 | |
| SCHEMBL30014371 | 0.87 | PDE4B (0.43) | TSHRNPSR1HSD11B1MGLLLIPG | |
| SCHEMBL23134613 | 0.87 | TSHR (0.40) | TSHRNPSR1HSD11B1MGLLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223034-A1 | SOS1 DEGRADATION AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |