Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 10/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032902 | 0.83 | HSP90AA1 (0.48) | HSP90AA1 | |
| SCHEMBL30033577 | 0.82 | CYP11B1 (0.39) | HSP90AA1MALT1 | |
| SCHEMBL30032801 | 0.82 | BCAT2 (0.39) | CYP17A1HSP90AA1MALT1 | |
| SCHEMBL30032253 | 0.81 | DDR1 (0.40) | HSP90AA1MALT1 | |
| SCHEMBL30033591 | 0.78 | NPEPPS (0.40) | HSP90AA1MALT1 | |
| SCHEMBL30032960 | 0.78 | HSP90AA1 (0.36) | CYP17A1HSP90AA1MALT1 | |
| SCHEMBL30033454 | 0.78 | MALT1 (0.44) | MALT1 | |
| SCHEMBL30034350 | 0.77 | NPEPPS (0.42) | HSP90AA1 | |
| SCHEMBL30032796 | 0.75 | CYP11B2 (0.46) | CYP17A1HSP90AA1MALT1 | |
| SCHEMBL31509793 | 0.75 | NPEPPS (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |