Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032977 | 1.00 | NPEPPS (0.40) | NPEPPSKDM4EHTTHSD17B10PKM | |
| SCHEMBL30033426 | 0.89 | NPEPPS (0.43) | NPEPPSKDM4EHTTHSD17B10PKM | |
| SCHEMBL30034219 | 0.89 | NPEPPS (0.43) | NPEPPSKDM4EHTTHSD17B10PKM | |
| SCHEMBL30034350 | 0.82 | NPEPPS (0.42) | NPEPPSKDM4EHTTHSD17B10PKM | |
| SCHEMBL30032902 | 0.82 | HSP90AA1 (0.48) | NPEPPSKDM4EHTTHSP90AA1DDR1 | |
| SCHEMBL30033459 | 0.80 | PKM (0.43) | NPEPPSKDM4EHTTHSD17B10PKM | |
| SCHEMBL31509793 | 0.79 | NPEPPS (0.57) | NPEPPSKDM4EHTTHSD17B10PKM | |
| SCHEMBL30033042 | 0.79 | KDM4E (0.57) | NPEPPSKDM4EHTTHSD17B10PKM | |
| SCHEMBL30032168 | 0.79 | NPEPPS (0.49) | NPEPPSKDM4EHTTHSD17B10PKM | |
| SCHEMBL30032220 | 0.78 | NPEPPS (0.42) | NPEPPSKDM4EHTTHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |