Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844187 | 0.82 | MAPK1 (0.47) | MAPK1BRD4CREBBPP2RX7NPC1 | |
| SCHEMBL30044769 | 0.80 | SPTLC1 (0.49) | BRD4CREBBPP2RX7TRPM2HPGD | |
| SCHEMBL28818541 | 0.79 | MAPK1 (0.49) | MAPK1BRD4CREBBPP2RX7 | |
| SCHEMBL30045599 | 0.78 | P2RX7 (0.40) | BRD4CREBBPP2RX7TRPM2HPGD | |
| SCHEMBL21995408 | 0.75 | LMNA (0.42) | MAPK1SMN1; SMN2HRH2HRH1 | |
| SCHEMBL2977256 | 0.73 | MAPK1 (0.57) | MAPK1BRD4CREBBPP2RX7NPC1 | |
| SCHEMBL2969795 | 0.73 | MAPK1 (0.77) | MAPK1BRD4CREBBPNPC1KCNK3 | |
| SCHEMBL6439340 | 0.70 | NPC1 (0.53) | MAPK1BRD4CREBBPNPC1 | |
| SCHEMBL30853597 | 0.70 | RBP4 (0.56) | RBP4 | |
| SCHEMBL30045088 | 0.69 | MAPT (0.54) | MAPK1NPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081509-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Zydus Lifesciences Limited (IN) | 2022-11-02 | — | — | EP | disclosed |