Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25341026 | 1.00 | GPR119 (0.48) | GPR119LMNANR1H2KDM4EPKM | |
| SCHEMBL25341031 | 1.00 | GPR119 (0.48) | GPR119LMNANR1H2KDM4EPKM | |
| SCHEMBL25341028 | 1.00 | GPR119 (0.48) | GPR119LMNANR1H2KDM4EPKM | |
| SCHEMBL25969339 | 0.91 | LMNA (0.52) | GPR119LMNANR1H2KDM4EPKM | |
| SCHEMBL25969338 | 0.91 | LMNA (0.52) | GPR119LMNANR1H2KDM4EPKM | |
| SCHEMBL25969337 | 0.91 | LMNA (0.52) | GPR119LMNANR1H2KDM4EPKM | |
| SCHEMBL25339595 | 0.83 | LMNA (0.51) | LMNARIPK1CHRM3 | |
| SCHEMBL25339589 | 0.83 | LMNA (0.51) | LMNARIPK1CHRM3 | |
| SCHEMBL25339600 | 0.83 | LMNA (0.51) | LMNARIPK1CHRM3 | |
| SCHEMBL20208338 | 0.82 | LMNA (0.70) | GPR119LMNANR1H2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055133-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | WAVE LIFE SCIENCES LTD (SG) | 2026-02-26 | — | — | US | disclosed |
| US-12428442-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2025-09-30 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-20220356204-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | WAVE LIFE SCIENCES LTD. (SG) | 2022-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | GPR119 700/4885LMNA 434/4885NR1H2 4436/4885 |
| US-20220356204-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | ALKBH1, DUT, RNGTT | GPR119 700/4885LMNA 434/4885NR1H2 4436/4885 |
| US-12428442-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | GPR119 700/4885LMNA 434/4885NR1H2 4436/4885 |
| US-20260055133-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | NSUN2, NSUN3, NOP2 | GPR119 2320/4885LMNA 284/4885NR1H2 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.