Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.58 |
| ▸ | FAAH | O00519 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CCR6 | P51684 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491247 | 0.81 | MGLL (0.60) | MGLLFAAHHSP90AA1PKMMEN1 | |
| SCHEMBL8026859 | 0.81 | MGLL (0.63) | MGLLFAAHHSP90AA1PKMMEN1 | |
| SCHEMBL28752498 | 0.80 | MGLL (0.62) | MGLLFAAHHSP90AA1PKMMEN1 | |
| SCHEMBL29510581 | 0.80 | MGLL (0.62) | MGLLFAAHHSP90AA1PKMMEN1 | |
| SCHEMBL24997232 | 0.79 | POLB (0.59) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL21383412 | 0.79 | L3MBTL1 (0.54) | MEN1KMT2AALDH1A1POLBL3MBTL1 | |
| SCHEMBL331752 | 0.77 | MGLL (0.84) | MGLLFAAHHSP90AA1PKMMEN1 | |
| SCHEMBL4385482 | 0.77 | MGLL (0.84) | MGLLFAAHHSP90AA1PKMMEN1 | |
| SCHEMBL487033 | 0.77 | MGLL (0.84) | MGLLFAAHHSP90AA1PKMMEN1 | |
| SCHEMBL28745022 | 0.77 | MEN1 (0.49) | MEN1KMT2APOLBL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114432301-B | Covalent inhibitor derivative and application thereof in treatment of viral infection | 北京大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-114432301-A | Covalent inhibitor derivative and application thereof in treating virus infection | 北京大学 | 2022-05-06 | — | — | CN | disclosed |
| EP-2709984-B1 | NEW HEXAHYDROCYCLOPENTAPYRROLONE, HEXAHYDROPYRROLOPYRROLONE, OCTAHYDROPYRROLOPYRIDINONE AND OCTAHYDROPYRIDINONE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2015-03-18 | — | — | EP | disclosed |
| EP-2709984-A1 | NEW HEXAHYDROCYCLOPENTAPYRROLONE, HEXAHYDROPYRROLOPYRROLONE, OCTAHYDROPYRROLOPYRIDINONE AND OCTAHYDROPYRIDINONE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-03-26 | — | — | EP | disclosed |
| US-8501768-B2 | Hexahydrocyclopentapyrrolone, hexahydropyrrolopyrrolone, octahydropyrrolopyridinone and octahydropyridinone compounds | HOFFMANN-LA ROCHE INC. (US) | 2013-08-06 | — | — | US | disclosed |
| US-20120295934-A1 | New Hexahydrocyclopentapyrrolone, Hexahydropyrrolopyrrolone, Octahydropyrrolopyridinone and Octahydropyridinone Compounds | F. HOFFMANN-LA ROCHE AG (CH) | 2012-11-22 | — | — | US | disclosed |
| WO-2012156339-A1 | NEW HEXAHYDROCYCLOPENTAPYRROLONE, HEXAHYDROPYRROLOPYRROLONE, OCTAHYDROPYRROLOPYRIDINONE AND OCTAHYDROPYRIDINONE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-11-22 | — | — | WO | disclosed |
| US-7787085-B2 | Optical alignment method and liquid crystal display element | JSR CORPORATION (JP) | 2010-08-31 | — | — | US | disclosed |
| CN-100412161-C | Liquid crystal aligning agent and liquid crystal display element | JSR CORP (JP) | 2008-08-20 | — | — | CN | disclosed |
| US-20080123046-A1 | OPTICAL ALIGNMENT METHOD AND LIQUID CRYSTAL DISPLAY ELEMENT | JSR CORPORATION (JP) | 2008-05-29 | — | — | US | disclosed |
| CN-100344731-C | Liquid crystal aligning agent and liquid crystal display element | JSR CORP (JP) | 2007-10-24 | — | — | CN | disclosed |
| US-7074344-B2 | Liquid crystal aligning agent and liquid crystal display element | JSR CORPORATION (JP) | 2006-07-11 | — | — | US | disclosed |
| CN-1721502-A | Liquid crystal aligning agent and liquid crystal display element | JSR CORP (JP) | 2006-01-18 | — | — | CN | disclosed |
| US-20050259203-A1 | Optical alignment method and liquid crystal display element | JSR CORPORATION (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1353217-A1 | Optical alignment method and liquid crystal display element | JSR Corporation (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-20030087045-A1 | Liquid crystal aligning agent and liquid crystal display element | JSR CORPORATION (JP) | 2003-05-08 | — | — | US | disclosed |
| CN-1408817-A | Liquid crystal aligning agent and liquid crystal display element | JSR CORP (JP) | 2003-04-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295934-A1 | New Hexahydrocyclopentapyrrolone, Hexahydropyrrolopyrrolone, Octahydropyrrolopyridinone and Octahydropyridinone Compounds | LIPE, LIPC, PNLIP | MGLL 8/4885FAAH 223/4885HSP90AA1 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.