Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.50 |
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722916 | 0.86 | MAPT (0.54) | NOS1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL84462 | 0.85 | TRPA1 (0.54) | ROCK2NOS1ROCK1MAPTKDM4E | |
| SCHEMBL22079235 | 0.82 | ROCK2 (0.55) | ROCK2NOS1ROCK1MAPTKDM4E | |
| SCHEMBL1754871 | 0.82 | ROCK2 (0.55) | ROCK2NOS1ROCK1MAPTKDM4E | |
| SCHEMBL20841219 | 0.82 | NOS1 (0.55) | ROCK2NOS1ROCK1MAPTKDM4E | |
| SCHEMBL27995719 | 0.82 | NOS1 (0.55) | ROCK2NOS1ROCK1MAPTKDM4E | |
| SCHEMBL263567 | 0.82 | ROCK2 (0.55) | ROCK2NOS1ROCK1MAPTKDM4E | |
| SCHEMBL29520764 | 0.81 | TRPA1 (0.54) | ROCK2NOS1ROCK1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL28598925 | 0.81 | ROCK2 (0.53) | ROCK2NOS1ROCK1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL29915566 | 0.81 | ROCK2 (0.53) | ROCK2NOS1ROCK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530189-B2 | Carbamate compounds and methods of making and using same | H. LUNDBECKA/S (DK) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530189-B2 | Carbamate compounds and methods of making and using same | ABHD6, ABHD16A, RABL6 | ROCK2 3084/4885NOS1 2113/4885ROCK1 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.