Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.60 |
| ▸ | DRD3 | P35462 | 11/20 | 0.60 |
| ▸ | DRD4 | P21917 | 4/20 | 0.60 |
| ▸ | DRD1 | P21728 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 7/20 | 0.53 |
| ▸ | HTR1A | P08908 | 6/20 | 0.53 |
| ▸ | HTR7 | P34969 | 5/20 | 0.53 |
| ▸ | HTR6 | P50406 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983420 | 0.81 | HTR1A (0.55) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL8828516 | 0.81 | DRD2 (0.51) | DRD2DRD3HTR2AHTR1AHTR7 | |
| SCHEMBL3174237 | 0.80 | CHEK1 (0.47) | DRD2DRD3HTR2A | |
| SCHEMBL8557009 | 0.80 | CHEK1 (0.47) | HTR2A | |
| SCHEMBL7986525 | 0.79 | CCR3 (0.56) | — | |
| SCHEMBL8554507 | 0.79 | SIGMAR1 (0.47) | HTR2A | |
| SCHEMBL8667745 | 0.79 | WEE1 (0.40) | DRD2DRD3HTR2AHTR1AHTR7 | |
| SCHEMBL7986154 | 0.78 | HTR1A (0.53) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL4910767 | 0.78 | CHEK1 (0.50) | DRD2HTR1AHTR6 | |
| SCHEMBL8558051 | 0.77 | CHEK1 (0.49) | DRD2HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109419802-B | Compounds having dopamine D3 receptor modulating activity and uses thereof | 中国人民解放军军事医学科学院毒物药物研究所（CN） | 2023-01-13 | — | — | CN | disclosed |