Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL27563472 | 0.84 | GAA (0.54) | ALDH1A1TSHRCYP3A4CYP2D6GAA | |
| Cyclopropane SCHEMBL2101355 | 0.84 | GAA (0.54) | ALDH1A1TSHRCYP3A4CYP2D6GAA | |
| Cyclohexanol SCHEMBL1553521 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4CYP2D6ADORA3 | |
| Phosphine SCHEMBL28194487 | 0.82 | GAA (0.52) | ALDH1A1TSHRCYP3A4CYP2D6GAA | |
| SCHEMBL6958251 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4CYP2D6ADORA3 | |
| Cyclohexylamine SCHEMBL11787101 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4CYP2D6ADORA3 | |
| Cyclopentanol SCHEMBL1554394 | 0.81 | CYP2D6 (0.51) | ALDH1A1TSHRCYP3A4CYP2D6ADORA3 | |
| SCHEMBL4824258 | 0.81 | CYP2D6 (0.51) | ALDH1A1TSHRCYP3A4CYP2D6ADORA3 | |
| SCHEMBL1500503 | 0.81 | LMNA (0.49) | ALDH1A1TSHRPOLBKDM4ELMNA | |
| SCHEMBL631325 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRCYP3A4CYP2D6ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501985-B2 | Use of phosphonium salts in coupling reactions and process for their manufacture | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) | 2013-08-06 | — | — | US | claimed |
| US-20100197969-A1 | USE OF PHOSPHONIUM SALTS IN COUPLING REACTIONS AND PROCESS FOR THEIR MANUFACTURE | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) | 2010-08-05 | — | — | US | claimed |
| WO-2009013628-A2 | USE OF PHOSPHONIUM SALTS IN COUPLING REACTIONS AND PROCESS FOR THEIR MANUFACTURE | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) | 2009-01-29 | — | — | WO | claimed |
| EP-2019107-A1 | Use of phosphonium salts in coupling reactions and process for their manufacture | Dynamit Nobel GmbH Explosivstoff- und Systemtechnik (DE) | 2009-01-28 | — | — | EP | claimed |
| CN-1554680-A | In mold addition polymerization composition of norbornene-type monomers and its crosslinking addition polymer | ס�ѵ�ľ��ʽ���� | 2004-12-15 | — | — | CN | claimed |
| CN-1333788-A | In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes | GOODRICH CO B F (US) | 2002-01-30 | — | — | CN | claimed |
| CN-120152955-A | Compositions comprising isomer mixtures of itaconimide norbornene and citraconimide norbornene | 3M创新有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-117295752-A | Monomers, polymerizable compositions, and polymers derived therefrom | 3M创新有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-116490538-A | Curable composition, syntactic foam, method of preparing syntactic foam, and article comprising syntactic foam | 3M创新有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-8501985-B2 | Use of phosphonium salts in coupling reactions and process for their manufacture | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) | 2013-08-06 | — | — | US | disclosed |
| US-20100197969-A1 | USE OF PHOSPHONIUM SALTS IN COUPLING REACTIONS AND PROCESS FOR THEIR MANUFACTURE | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) | 2010-08-05 | — | — | US | disclosed |
| WO-2009013628-A2 | USE OF PHOSPHONIUM SALTS IN COUPLING REACTIONS AND PROCESS FOR THEIR MANUFACTURE | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) | 2009-01-29 | — | — | WO | disclosed |
| EP-2019107-A1 | Use of phosphonium salts in coupling reactions and process for their manufacture | Dynamit Nobel GmbH Explosivstoff- und Systemtechnik (DE) | 2009-01-28 | — | — | EP | disclosed |
| US-20070123667-A1 | PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER | JSR CORPORATION (JP) | 2007-05-31 | — | — | US | disclosed |
| EP-1712572-A1 | PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER | JSR Corporation (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-20060217505-A1 | Process for producing cycloolefin addition polymer | JRS CORPORATION (JP) | 2006-09-28 | — | — | US | disclosed |
| EP-1657259-A1 | PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER | JSR Corporation (JP) | 2006-05-17 | — | — | EP | disclosed |
| CN-1555387-A | Polymer composition for manufacturing optical waveguide, optical waveguide manufactured thereby, and method for manufacturing the waveguide | 古德里奇公司 | 2004-12-15 | — | — | CN | disclosed |
| CN-1554680-A | In mold addition polymerization composition of norbornene-type monomers and its crosslinking addition polymer | ס�ѵ�ľ��ʽ���� | 2004-12-15 | — | — | CN | disclosed |
| CN-1333788-A | In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes | GOODRICH CO B F (US) | 2002-01-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197969-A1 | USE OF PHOSPHONIUM SALTS IN COUPLING REACTIONS AND PROCESS FOR THEIR MANUFACTURE | PPIP5K2, PHOSPHO1, PNKP | ALDH1A1 4586/4885TSHR 3068/4885CYP3A4 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.