SCHEMBL30103212

SCHEMBL30103212

O=c1c2cc(F)ccc2nc(Nc2cccnc2)n1-c1ccccc1F

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 2/20 0.48
IDO2 Q6ZQW0 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.43
GLA P06280 1/20 0.43
IDO1 P14902 1/20 0.42
RAD52 P43351 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23958205 1.00 TDO2 (0.48) TDO2IDO2L3MBTL1GLAIDO1
SCHEMBL30103275 0.91 TDO2 (0.48) TDO2IDO2L3MBTL1IDO1
SCHEMBL30103230 0.91
SCHEMBL23958262 0.91
SCHEMBL23958208 0.91 TDO2 (0.48) TDO2IDO2L3MBTL1IDO1
SCHEMBL23958265 0.90 PIK3CD (0.46) TDO2IDO2IDO1RAD52KMT2A
SCHEMBL29738614 0.90 PIK3CD (0.46) TDO2IDO2IDO1RAD52KMT2A
SCHEMBL24110936 0.89 TUBB4A (0.43) RAD52KMT2A
SCHEMBL30103299 0.89 TUBB4A (0.43) RAD52KMT2A
SCHEMBL23958283 0.89 HTR7 (0.46) TDO2IDO2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115427399-A 2-heteroarylaminoquinazolinone derivatives 住友制药株式会社 2022-12-02 CN claimed
CN-115427399-A 2-heteroarylaminoquinazolinone derivatives 住友制药株式会社 2022-12-02 CN disclosed