Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.54 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27981110 | 0.84 | CTSD (0.51) | MAPTKMT2ALMNAPOLBGAA | |
| SCHEMBL28319996 | 0.84 | TSHR (0.50) | MAPTKMT2ALMNAMEN1PLIN1 | |
| SCHEMBL18328499 | 0.84 | LMNA (0.52) | MAPTKMT2ALMNAMEN1PLIN1 | |
| SCHEMBL30104122 | 0.82 | ALDH1A1 (0.49) | MAPTKMT2ALMNAMEN1PLIN1 | |
| SCHEMBL22981059 | 0.81 | TSHR (0.46) | MAPTKMT2ALMNAMEN1GAA | |
| SCHEMBL29524844 | 0.81 | TSHR (0.46) | MAPTKMT2ALMNAMEN1GAA | |
| SCHEMBL4589656 | 0.80 | KMT2A (0.60) | MAPTKMT2ALMNAMEN1PLIN1 | |
| SCHEMBL30322741 | 0.80 | KMT2A (0.60) | MAPTKMT2ALMNAMEN1PLIN1 | |
| SCHEMBL18740870 | 0.80 | STAT3 (0.50) | MAPTKMT2ACTSDSMN1; SMN2HPGD | |
| SCHEMBL30104115 | 0.79 | HCRTR1 (0.54) | MAPTKMT2ALMNAMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518768-B2 | Artificial metalloenzymes containing noble metal-porphyrins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518768-B2 | Artificial metalloenzymes containing noble metal-porphyrins | PPIH, HMBS, PPOX | MAPT 3431/4885KMT2A 1549/4885LMNA 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.