Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18740988 | 0.85 | HCRTR1 (0.53) | HCRTR1KCNK3KCNK9MAPTMAPK1 | |
| SCHEMBL316291 | 0.85 | SGMS2 (0.53) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL27981110 | 0.84 | CTSD (0.51) | KCNK3KCNK9MAPTMAPK1GAA | |
| SCHEMBL29245038 | 0.80 | HCRTR1 (0.61) | HCRTR1KCNK3KCNK9MAPTMAPK1 | |
| SCHEMBL30104126 | 0.79 | MAPT (0.54) | KCNK3KCNK9MAPTMAPK1GAA | |
| SCHEMBL22982111 | 0.78 | GAA (0.44) | MAPTGAAKMT2AKDM4ELMNA | |
| SCHEMBL28319862 | 0.78 | NPC1 (0.44) | KCNK3KCNK9MAPTMEN1KMT2A | |
| SCHEMBL24766012 | 0.77 | HCRTR1 (0.58) | HCRTR1KCNK3KCNK9MAPTMAPK1 | |
| SCHEMBL14639033 | 0.76 | LMNA (0.50) | MAPTKMT2AKDM4ETSHRLMNA | |
| SCHEMBL1989129 | 0.76 | HCRTR1 (0.65) | HCRTR1KCNK3KCNK9MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518768-B2 | Artificial metalloenzymes containing noble metal-porphyrins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518768-B2 | Artificial metalloenzymes containing noble metal-porphyrins | PPIH, HMBS, PPOX | HCRTR1 4807/4885KCNK3 2705/4885KCNK9 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.