Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.59 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153909 | 0.83 | CCKBR (0.59) | CCKBRCTSVCTSLCTSBCTSS | |
| SCHEMBL6154193 | 0.78 | CCKBR (0.64) | CCKBRCTSVCTSLCTSBCTSS | |
| SCHEMBL30104881 | 0.76 | ALDH1A1 (0.48) | CCKBRTHRBMAPK1ALDH1A1 | |
| SCHEMBL30104867 | 0.74 | MAPK1 (0.47) | CCKBRCTSBTHRBMAPK1LMNA | |
| SCHEMBL30104893 | 0.72 | CCKBR (0.41) | CCKBRCTSVCTSLCTSBCTSS | |
| SCHEMBL30104898 | 0.71 | CCKBR (0.41) | CCKBRTHRBMAPK1LMNAALDH1A1 | |
| SCHEMBL28735046 | 0.70 | ALDH1A1 (0.46) | CCKBRCTSVCTSLCTSBCTSS | |
| SCHEMBL6154302 | 0.70 | CCKBR (0.46) | CCKBRCTSVCTSLCTSBCTSS | |
| SCHEMBL30104899 | 0.70 | CCKBR (0.38) | CCKBRCTSBTHRBMAPK1LMNA | |
| SCHEMBL30104880 | 0.70 | NUAK1 (0.35) | CCKBRTHRBMAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583927-B | Thioether compound, and preparation method and application thereof | 华南师范大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-115583927-A | Thioether compound and preparation method and application thereof | 华南师范大学 | 2023-01-10 | — | — | CN | disclosed |