SCHEMBL30104893

SCHEMBL30104893

O=C1OC(OCc2ccccc2)C(SCc2ccccc2)=C1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 1/20 0.41
CTSV O60911 1/20 0.35
CTSL P07711 1/20 0.35
CTSB P07858 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
CTSC P53634 1/20 0.35
CTSF Q9UBX1 1/20 0.35
DAO P14920 4/20 0.35
LMNA P02545 2/20 0.35
KDM6B O15054 1/20 0.34
KDM4A O75164 1/20 0.34
KDM4D Q6B0I6 1/20 0.34
HIF1AN Q9NWT6 1/20 0.34
KDM5B Q9UGL1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34
MAOB P27338 2/20 0.33
PDPK1 O15530 1/20 0.33
MTOR P42345 1/20 0.33
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30104840 0.88 NR2E3 (0.37) CCKBRCTSBDAOLMNAMAOB
SCHEMBL30104902 0.84 S100A4 (0.37) CTSBDAOLMNAMAOBELANE
SCHEMBL30104876 0.83 CTSB (0.36) CTSBLMNAALDH1A1S100A4SMN1; SMN2
SCHEMBL30104872 0.81 POLB (0.38) CCKBRDAOLMNAMAOBALDH1A1
SCHEMBL6154302 0.79 CCKBR (0.46) CCKBRCTSVCTSLCTSBCTSS
SCHEMBL30104905 0.78 NPSR1 (0.37) CTSBDAOLMNAALDH1A1
SCHEMBL6155062 0.74 CCKBR (0.51) CCKBRCTSVCTSLCTSBCTSS
SCHEMBL30104874 0.72 CCKBR (0.59) CCKBRCTSVCTSLCTSBCTSS
SCHEMBL30104867 0.71 MAPK1 (0.47) CCKBRCTSBDAOLMNAALDH1A1
SCHEMBL30104898 0.68 CCKBR (0.41) CCKBRDAOLMNAMAOBELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583927-B Thioether compound, and preparation method and application thereof 华南师范大学 2024-07-12 CN disclosed
CN-115583927-A Thioether compound and preparation method and application thereof 华南师范大学 2023-01-10 CN disclosed