Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104898 | 0.86 | CCKBR (0.41) | MAPK1THRBALDH1A1CCKBRMAPT | |
| SCHEMBL30104840 | 0.84 | NR2E3 (0.37) | MAPK1THRBALDH1A1CCKBRNR2E3 | |
| SCHEMBL30104899 | 0.82 | CCKBR (0.38) | MAPK1THRBALDH1A1CCKBRPOLB | |
| SCHEMBL30104881 | 0.78 | ALDH1A1 (0.48) | MAPK1THRBALDH1A1CCKBRPOLB | |
| SCHEMBL30104874 | 0.74 | CCKBR (0.59) | MAPK1THRBALDH1A1CCKBRMAPT | |
| SCHEMBL30104876 | 0.72 | CTSB (0.36) | MAPK1ALDH1A1NR2E3MAPTS100A4 | |
| SCHEMBL30104893 | 0.71 | CCKBR (0.41) | ALDH1A1CCKBRS100A4LMNASMN1; SMN2 | |
| SCHEMBL30104902 | 0.69 | S100A4 (0.37) | MAPK1ALDH1A1MAPTPKMS100A4 | |
| SCHEMBL14505731 | 0.69 | ALDH1A1 (0.51) | MAPK1THRBALDH1A1CCKBRPOLB | |
| SCHEMBL30104872 | 0.67 | POLB (0.38) | ALDH1A1CCKBRPOLBS100A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583927-B | Thioether compound, and preparation method and application thereof | 华南师范大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-115583927-A | Thioether compound and preparation method and application thereof | 华南师范大学 | 2023-01-10 | — | — | CN | disclosed |