Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metahexamide SCHEMBL218071 | 1.00 | ADORA3 (0.68) | ADORA3ALDH1A1LMNATSHRBLM | |
| Metahexamide SCHEMBL15845574 | 0.85 | ADORA3 (0.62) | ADORA3ALDH1A1LMNATSHRBLM | |
| Gliclazide SCHEMBL13723694 | 0.85 | ALDH1A1 (0.67) | ADORA3ALDH1A1LMNATSHRBLM | |
| SCHEMBL23736042 | 0.81 | ADORA3 (0.74) | ADORA3ALDH1A1LMNATSHRBLM | |
| Glycyclamide SCHEMBL49386 | 0.81 | ADORA3 (1.00) | ADORA3ALDH1A1LMNATSHRBLM | |
| Heptolamide SCHEMBL1814750 | 0.81 | ADORA3 (1.00) | ADORA3ALDH1A1LMNATSHRBLM | |
| Glyoctamide SCHEMBL667731 | 0.81 | ADORA3 (1.00) | ADORA3ALDH1A1LMNATSHRBLM | |
| Glycyclamide SCHEMBL21722119 | 0.80 | ADORA3 (0.97) | ADORA3ALDH1A1LMNATSHRBLM | |
| Hydrochloric Acid SCHEMBL9796358 | 0.80 | ALDH1A1 (0.71) | ALDH1A1LMNATSHRTDP1GAA | |
| Tolpentamide SCHEMBL2109411 | 0.80 | ADORA3 (0.97) | ADORA3ALDH1A1LMNATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255995-A1 | Nicotinyl Riboside Compounds and Their Uses | MITOPOWER LLC | 2023-08-17 | — | — | US | disclosed |
| US-11541028-B2 | Peptide pharmaceuticals for treatment of NASH and other disorders | ALTIMMUNE INC. (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255995-A1 | Nicotinyl Riboside Compounds and Their Uses | NADK, NNT, NAMPT | ADORA3 1000/4885ALDH1A1 1331/4885LMNA 800/4885 |
| US-11541028-B2 | Peptide pharmaceuticals for treatment of NASH and other disorders | GLP1R, IAPP, GPR119 | ADORA3 4323/4885ALDH1A1 4670/4885LMNA 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.