Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | AGXT | P21549 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538190 | 0.90 | HTR7 (0.75) | HTR1AHTR7USP2HSD17B10MAPK1 | |
| SCHEMBL24061149 | 0.88 | ADRA2C (0.57) | HTR1AHTR7ADRA2CHTR3AAGXT | |
| SCHEMBL26378183 | 0.84 | ADRA2C (0.53) | HTR1AHTR7ADRA2CHTR3AAGXT | |
| SCHEMBL30108226 | 0.82 | MELK (0.60) | ADRA2CHTR3AALDH1A1SMN1; SMN2 | |
| SCHEMBL27497441 | 0.82 | HTR1A (0.70) | HTR1AHTR7AGXTUSP2HSD17B10 | |
| SCHEMBL7610501 | 0.82 | HTR7 (0.60) | HTR1AHTR7USP2HSD17B10MAPK1 | |
| SCHEMBL149502 | 0.82 | KMT2A (0.61) | HTR1AADRA2CHTR3AHSD17B10MAPK1 | |
| SCHEMBL23220824 | 0.82 | KMT2A (0.61) | HTR1AADRA2CHTR3AHSD17B10MAPK1 | |
| SCHEMBL23220843 | 0.82 | KMT2A (0.61) | HTR1AADRA2CHTR3AHSD17B10MAPK1 | |
| SCHEMBL7498216 | 0.81 | ADRB1 (0.61) | HTR1AHTR7USP2HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-01-14 | — | — | US | claimed |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | MERTK, ERBB2, SRC | HTR1A 2823/4885HTR7 1904/4885ADRA2C 496/4885 |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | HTR1A 2823/4885HTR7 1904/4885ADRA2C 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.