Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957007 | 0.92 | MEN1 (0.45) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL13959822 | 0.90 | MEN1 (0.54) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL30299043 | 0.90 | MAOA (0.53) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL13960156 | 0.90 | MEN1 (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL16379307 | 0.90 | MEN1 (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL3025341 | 0.89 | MAOA (0.44) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL570033 | 0.88 | MEN1 (0.50) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL9354709 | 0.83 | MEN1 (0.51) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8194926 | 0.83 | MEN1 (0.56) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL13247436 | 0.82 | MEN1 (0.47) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189656-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-07-29 | — | — | US | disclosed |
| US-20100189656-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-07-29 | — | — | US | disclosed |
| WO-2009005364-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-01-08 | — | — | WO | disclosed |
| WO-2009005364-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189656-A1 | CONTRAST AGENTS | IPO4, TPO, IPO11 | MEN1 102/4885GAA 3415/4885KMT2A 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.